Health Indicator Report of Hereditary Breast and Ovarian Cancer
Hereditary cancer syndromes are genetic predispositions for certain types of cancer that can be passed down through generations. Hereditary Breast and Ovarian Cancer Syndrome (HBOC) is caused by mutations in the BRCA1 and BRCA2 genes and is associated with an increased risk of breast and ovarian cancer. BRCA mutations increase a woman's risk of breast cancer by 45-65% and ovarian cancer by 10-39%.^1^ Men with BRCA mutations are also at an increased risk for breast cancer, especially if they have a BRCA2 mutation.^1^ While hereditary cancers only account for about 10% of all cancers, people with family history of hereditary cancers are at higher risk for getting cancer more than once in their lifetimes, more likely to get cancer at a younger age, and more likely to be diagnosed when the cancer is at a later, more advanced stage.^2^
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1. Centers for Disease Control and Prevention. (2014, Mar 06). More detailed information on key tier 1 applications - Hereditary breast and ovarian cancer (HBOC). [https://www.cdc.gov/genomics/implementation/toolkit/hboc_1.htm]
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2. Centers for Disease Control and Prevention. (2020, Aug 03). Cancer genomics program. [[https://www.cdc.gov/cancer/dcpc/about/genomics/index.htm]
Breast Cancer Under Age 50 Incidence by Year, Utah and U.S., 1999-2018
Notes
Age-adjusted to U.S. 2000 standard population.Data Sources
- Population Estimates: National Center for Health Statistics (NCHS) through a collaborative agreement with the U.S. Census Bureau, IBIS Version 2021
- Cancer data provided by the Utah Cancer Registry, supported by the National Cancer Institute (HHSN261201800016I), the U.S. Center for Disease Control and Prevention (NU58DP0063200), the University of Utah, and Huntsman Cancer Foundation
- U.S. Cancer Statistics: WONDER Online Database. United States Department of Health and Human Services, Centers for Disease Control and Prevention and National Cancer Institute. Accessed at [http://wonder.cdc.gov/cancer.html]
- by Year, Utah and U.S., 1999-2018
- by Local Health District, Utah, 2014-2018
- by Ethnicity, Utah, 2014-2018
- by Race, Utah, 2013-2018
- by Local Health District, Utah, 2014-2018
- by Year, Utah and U.S., 1999-2018
- Incidence Rate by Year, Utah 2010-2018
- Utah 2016, 2018, 2020
- Utah 2015, 2016, 2018, 2020
- Utah 2015, 2016, 2018, 2020
- Utah 2016, 2018, 2020
Definition
The rate of breast or ovarian cancer incidence in Utah or U.S. per 100,000 females.Numerator
The number of breast or ovarian cancer cases among Utah or U.S. for a specified time period.Denominator
The female population of Utah or U.S. for a specified time period.Healthy People Objective G-1:
Increase the proportion of women with a family history of breast and/or ovarian cancer who receive genetic counselingU.S. target: 38.1 percent
Other Objectives
'''Utah Cancer Action Network Targets for Change:'''[[br]] Reduce the rate of breast cancer diagnosed at an advanced (regional or distant) stage among women ages 40 to 74. [[br]] '''Utah 2020 Target:''' 80 per 100,000 womenHow Are We Doing?
Female breast cancer incidence under age 50 has not significantly changed over the years, however ovarian cancer incidence has increased in recent years.How Do We Compare With the U.S.?
Throughout the years, the Utah female breast cancer under age 50 incidence rate has been consistently lower than the U.S. rate. Ovarian cancer rate has continually fluctuated over the years with some years experiencing greater rates than the U.S. rate and some years lower.What Is Being Done?
The Utah Cancer Genomics Program (UCGP) collaborates with community organizations and health systems to provide public/provider education, improve referral processes, and improve access to genetic counseling and testing. These organizations reach many populations throughout the state and provide a variety of services. The UCGP holds and annual Request for Proposals (RFP) competitive application process and awards funding to innovative projects that have the potential to drive Policy, Systems, and Environmental change in public awareness of Family Health History and referral to and uptake of appropriate genetic services. This mini-grant enables strong partnerships between the UCGP and health systems, clinics, and community-based organizations and expands the program's reach into the community. In addition, the UCGP participates in the Utah Cancer Action Network (UCAN), a statewide partnership whose goal is to reduce the burden of cancer. The mission of UCAN is to lower cancer incidence and mortality in Utah through collaborative efforts directed toward cancer prevention and control. As a result of this planning process, objectives and strategies have been developed by community partners regarding the early detection of cervical, breast, and colorectal cancers and separate cancer genomics collaboration opportunities are also available.Available Services
The Utah Cancer Control Program (UCCP) provides free or low cost clinical breast exams and mammograms to women who meet age and income guidelines. Eligible women with abnormal screening exams are offered diagnostic evaluation by participating providers. As of July 1, 2001, the UCCP has been able to refer Utah women in need of treatment for breast and cervical cancers for full Medicaid benefits. Participants must meet all requirements as outlined in the National Breast and Cervical Cancer Treatment Act. Coverage of preventive screening tests including mammograms and clinical breast exams is required by the United States Preventive Services Task Force (USPSTF) created by the Affordable Care Act (ACA), as is genetic testing for BRCA1/2 variations associated with hereditary breast and ovarian cancer.Health Program Information
In 2014 the Utah Department of Health received funding from the CDC to implement a program focused on addressing the cancer burden associated with hereditary cancer syndromes. The UCGP continues to receive funding from the CDC for surveillance, education, improving access to and referrals to genetic services, and bolstering partnerships with healthcare organizations, non-profit organizations, and other community organizations.
Page Content Updated On 01/25/2022,
Published on 11/14/2022